gentisic acid การใช้

• The leaves also contain a range of hydroxybenzoic acids : gallic acid and its ethyl ester, gentisic acid, anthranilic acid, protocatechuic acid, and ellagic acid ( alizarine yellow ).
• At least as of 1985, the idea was that the salicylic acid is oxidized to gentisic acid by the peroxidase activity of PGH synthase, which in turn could be further oxidized to quinonoids which could covalently bond the cyclooxygenase.
• "' 3-Maleylpyruvic acid "', or "'3-maleylpyruvate "', is a dicarboxylic acid formed by the oxidative ring opening of gentisic acid by gentisate 1, 2-dioxygenase during the metabolism of tyrosine.
• It is these same hydrogen bonding functional groups that interact with and enhance the cocrystallization of Piracetam with gentisic acid, a non-steroidal anti-inflammatory drug ( NSAID ), and with p-hydroxybenzoic acid, an isomer of the aspirin precursor salicylic acid.
• Other identified components of bitterwood are : beta-carbolines, beta-sitostenone, beta-sitosterol, dehydroquassins, gallic acid, gentisic acid, hydroxyquassins, isoparain, isoparaines, isoquassins, malic acid, methylcanthins, methoxycanthins, methoxycantins, nigakilactone A, nor-neoquassin, parain, paraines, quassialactol, quassimarin, quassinol, quassol and simalikalactone D.
• Salicylates are excreted mainly by the kidneys as salicyluric acid ( 75 % ), free salicylic acid ( 10 % ), salicylic phenol ( 10 % ), and acyl glucuronides ( 5 % ), gentisic acid ( < 1 % ), and urinary pH . A 10-to 20-fold increase in renal clearance occurs when urine pH is increased from 5 to 8.